![]() ![]() One patient with DME (not CSDME) had significantly improved FPF after anti-VEGF treatment, demonstrating that this imaging modality may detect mechanisms not due to CSDME. 2 The results showed a strong correlation between decreased FPF and improvement in BCVA following therapy (Figure 1). In a study by Romo et al, eight patients with diabetic retinopathy (DR), diabetic macular edema (DME), and/or clinically significant DME (CSDME) were imaged before and after treatment with anti-VEGF therapy. The more intense the signal output the device generates, the more metabolic dysfunction it is measuring.Ĭonversely, a decrease in metabolic stress may reduce FPF intensity. 1 The amount of fluorescence emitted by the flavoprotein indicates reversible metabolic stress due to disease, before cell death. The device shines blue light onto the retina to excite flavoproteins, which show a green autofluorescence. ![]() The OcuMet Beacon (OcuSciences) identifies retinal metabolic diseases using flavoprotein fluorescence (FPF) technology. Here are some of the tools working their way through the ophthalmic imaging pipeline. As new imaging modalities emerge that tout advances in analytics, optics, and lasers, researchers are investigating their clinical utility before they become a part of routine practice. Super-resolution MRI, which can produce high-resolution images of the eye and lower scan times significantly, is particularly useful for myopic eyes.Īdvanced ocular imaging has transformed clinical eye care and is now integrated into the early detection, accurate diagnosis, and appropriate management of a variety of ocular diseases.Adaptive optics OCT has vastly improved and can be used for in vivo assessment of the retinal vasculature, cone function and density, and retinal pigment epithelium cell density.New imaging tools such as flavoprotein fluorescence technology, laser Doppler holography, photoacoustic imaging, and transscleral optical phase imaging are changing the way researchers see the retina and document ocular diseases. ![]()
0 Comments
Leave a Reply. |